经皮冠状动脉内支架植入术对外周血单核细胞NF
作者：王晖，杨志健，黄峻，朱铁兵，王连生，曹克将【关键词】 ,外周血单核细胞
Activation of NFκB induced by coronary stent placement in peripheral blood mononuclear cells
【Abstract】 AIM: To investigate the effect of coronary stenting on the activation of NFκB in peripheral blood mononuclear cells (PBMC). METHODS: Fifty patients were classified into two groups: 28 patients in stenttreatment group and 22 in coronary angiography (CAG). The levels of NFκB activity preprocedural and during the days after stent placement were determined using electrophoresis mobility shift assay (EMSA). RESULTS: The levels of NFκB activity in stenttreatment group from preprocedural to the 4th hour, 1st, 2nd and 3rd days after stent placement were (1.17±0.25) fold, (1.23±0.30) fold, (2.00±0.45) (2.49±0.46) fold and (2.25±0.4) fold respectively. Significantly increased levels of NFκB activity were seen in the 1st, 2nd and 3rd days (P
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