先天性心脏病合并肺动脉高压一氧化氮合酶mRNA表达及临床意义

时间：2024-06-09 23:34:02 药学毕业论文

作者：封加涛，苏艳玲，龚光甫，胡冬煦，曹亚
【关键词】心脏缺损,先天性；高血压,肺性；一氧化氮合酶；RNA,信使

【Abstract】 AIM: To explore the pathophysiological significance of nitric oxide(NO) and nitric oxide synthase(NOS) in congenital heart defects with pulmonary hypertension. METHODS: Twentyfour patients with congenital heart defects were divided into 3 groups: mild pulmonary hypertension group(n=8), moderate or severe pulmonary hypertension group(n=9), and nonpulmonary hypertension group(n=7). NOS mRNA expression was detected in lung tissues with reverse transcriptase polymerase chain reaction (RTPCR). RESULTS: The NOS mRNA expression levels in the patients with moderate or severe pulmonary hypertension were much lower than those in the ones with mildpulmonary hypertension or nonpulmonary hypertension (P

【先天性心脏病合并肺动脉高压一氧化氮合酶mRNA表达及临床意义】相关文章：

新生儿及小婴儿先天性心脏病的术后护理03-16

PRAME基因在急性白血病中的表达及临床意义分析03-08

正畸力作用下牙周炎大鼠牙周膜OPG/OPGL mRNA表达的实验研究03-30

辛伐他汀对肾移植后高脂血症患者RANTES及其受体CCR5 mRNA表达的03-02