皮肤鳞癌组织中MMP
【关键词】 皮肤肿瘤;免疫组织化学;明胶酶B;抗原CD34;微血管密度Expression of MMP9 in skin squamous cell carcinoma and its significance in microangiogenesis
【Abstract】 AIM: To detect the role and the significance of MMP9 in microangiogenesis in skin squamous cell carcinoma (SCC) and to observe the relation between the expression of MMP9 and microvessel density (MVD) in SCC. METHODS: Immunohistochemical SP staining was used to examine MMP9 expression and the change of MVD under light microscope in 45 cases of SCC, 19 cases of Bowen disease, and 10 cases of normal skin. RESULTS: The expression of MMP9 in SCC group was significantly higher than that in Bowen disease group(P
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